LUXT CONTROLS SPECIFIC QUORUM-SENSING-REGULATED BEHAVIORS IN VIBRIONACEAE SPP. VIA REPRESSION OF QRR1, ENCODING A SMALL REGULATORY RNA.

LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA.

Quorum sensing (QS) is a process of chemical communication bacteria use to transition between individual and collective behaviors.QS depends on the production, release, and synchronous response to signaling molecules called autoinducers (AIs).The marine bacterium Vibrio harveyi monitors AIs using a signal transduction pathway that relies on five sm

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Cystine/glutamate antiporter xCT deficiency reduces metastasis without impairing immune system function in breast cancer mouse models

Abstract Background The upregulation of antioxidant mechanisms is a common occurrence in cancer cells, as they strive to maintain balanced redox state and prevent oxidative damage.This includes the upregulation of the cystine/glutamate antiporter xCT, which plays a crucial role in protecting cancer cells from oxidative stress.Consequently, targetin

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